Get to know ‘Isala in Vitaminland’

How can the vaginal microbiome be linked to vitamins? Currently, the Isala team is immersed in the wonderful world of vitamin B2 thanks to Limosilactobacillus reuteri AMBV339. You probably got to know this vaginal bacterium in our previous blog. By now, we give you the unique opportunity to keep on following us on a fascinating vitamin journey! 😊

The Isala team takes a closer look at a variety of vaginal bacteria. It soon became clear that one of the many isolated bacteria received a special spot within our team. This bacterium was named Limosilactobacillus reuteri AMBV339. ‘AMBV339’ will certainly ring a bell to everyone in our lab and maybe to you as well after reading our previous blogpost. 😊 It could well be that you already recognized the name Limosilactobacillus, especially after the most recent update of new Isala results on our website.

Today, we want to continue introducing Limosilactobacillus reuteri AMBV339 to you. ‘AMB’ refers to the official name of our lab, namely Lab of Applied Microbiology and Biotechnology. The ‘V’ refers to the site where the bacterium was isolated from, which is the vagina, and this bacterium was the 339th vaginal bacterium that was isolated! L. reuteri AMBV339 is able to produce large amounts of vitamin B2 in a natural way. Compared to other lactobacilli, this has never been demonstrated before (which is really next level 😉).

A patent application was requested since such unique bacterial properties enable us to develop all kinds of innovative living products. After all, a patent is an important first step in case we ever want to develop new drugs or other biotech innovations. It protects intellectual property and enables to write down inventions and share them with the community. In case you want to learn more about the role of patents in the world of biotechnology and/or pharmacy, click here. Furthermore, the Isala team is working intensively on ethically responsible research. 😊 As such, we always look at possibilities in and availability for countries with a lower socio-economic status when applying for patents.

Obviously, when designing innovation possibilities with Limosilactobacillus reuteri AMV339, a great deal of fascinating laboratory research was involved. As mentioned earlier in our previous blog, we conducted many experiments to get to know this unique vaginal inhabitant better. Now we are looking forward to what future research has in store and we will certainly keep you informed! 😊

The vaginal swabs that we obtained from the Isala participants are further examined in our lab. In this way, we find out which bacteria are present and we learn more about their beneficial properties. Limosilactobacillus reuteri AMBV339 is one of them. This bacterium produces riboflavin (or vitamin B2). After a bunch of research and experiments, AMBV339 still surprises our Isala team members in a very positive manner!