Research

Curious about the course of the investigation? We totally understand that.  
On this page, you can read the broad outlines of the course of Isala. Be sure to sign up for our newsletter or follow Isala on social media for even more updates! 

October 2018

A more concrete idea

Sarah Lebeer submits a research proposal to the European Research Council (ERC) for groundbreaking research into lactobacilli’s useful role (Lacto-Be). This proposal aims to analyze lactobacilli in 1000 samples from the skin and the vagina for the first time. Therefore our citizen science expertise will have to be expanded much further. She has previously conducted citizen research on fermented roots and healthy bacteria in the nose. 

Sarah Ahannach starts her PhD

Another Sarah will join our research group. Sarah Ahannach is passionate about Women’s Health and is very passionate about researching the vaginal microbiome. 

October 2018
spring 2019

We see it bigger

Within Sarah Lebeer’s research group, the idea is growing further to focus more on creating ‘awareness’ around women’s vaginal health and breaking the associated taboos for the new citizen research into vaginal lactobacilli.

The scientific basis of our research is further developed

We do a lot of literature study, brainstorms, experiments, and analyses to prepare the research design. We gradually know what we want to measure and how we want to involve participants actively!

spring 2019
March 2019

Eline Oerlemans is receiving her PhD

During her Ph.D., she studied the importance of the vaginal microbiome. Interest within our research group is growing: we have to work on this! 

June 2019: This is the first time we sit down with our communications agency,  Studio Maria 

We are looking for 200 women who want to provide very intimate samples. Will this work?

June 2019
June 19, 2019

Defend project in Europe

Sarah Lebeer may defend the entire research design of lactobacilli’s useful role for the ERC (European Research Council).

Greenlight from Europe

We are getting good news from Europe; the broader research project has been approved, so Isala can now really start. There is a certainty that there will be a budget to analyze the samples. Isala must continue to look for funds to set up the complete citizen research.

September 3, 2019
September 2019

Our research is given a name and a logo

We choose Isala. A tribute to Isala Van Diest, the first female doctor in Belgium. We dare to choose a fun, eye-catching logo, panties.

Swabs, swabs, swabs!

We conduct numerous tests. Which type of swab is most suitable for our research? What points of attention are there for transport and storage? Which analysis technique gives the best results? 

October 2019
November 2019

Approaching stakeholders and writing files

You don’t do such a major citizen investigation alone, and there is a lot involved. We write files for the ethics committee, seek funding, and approach partners and stakeholders. Europe looks at all ethical and privacy aspects of our research.

The scientific and communicative dots on the i

We take our time for thorough preparation, both the scientific side of the research and the communication, because this is also crucial in citizen research. So we are conducting a pilot study with about twenty women. Is everything clear? Are all of their swabs usable for analysis? 

December 2019
January 14, 2020

First Isala Advisory Board

We provide an update on the study to all partners in Isala and ask for their advice.

Almost finished! 

We are working hard on the website and all communication materials for launching the search for 200 women. 

February 2020
March 8, 2020

Women’s day

Everything was ready to launch on this symbolic day, but there it was, COVID-19.

Gezocht: 200 vagina’s

Despite the corona crisis, we decide to launch our search for 200 participants. Few hours later, we have already achieved that goal. Wow! 

March 24, 2020
March 30, 2020

A proud ambassador

Evi Hanssen, a famous Belgian TV presenter, helps break the taboo around vaginal health and proudly poses in our lab

Massive enthusiasm

We are blown away by the success. As many as 5,528 women responded to our call. We close our launch phase with a smile. 

April 5, 2020
April 2020

Adjusting the research

The massive response offers many new possibilities. We decide to adjust our research completely. We will invite all women to take two vaginal samples. Everyone is given a lengthy questionnaire to complete. Again we are happy!

Busy times

We are changing everything and working very hard in our lab to get all the scientific material ready for this new research phase. All communication must also be adjusted and adapted. Suddenly, thousands of women will take two swabs instead of 200 participants in a long-term study…

May-June 2020
June 2020

You can also support Isala financially

The University Fund includes Isala. It is now possible to donate and support our research.

Get rid of the taboo!

We’re making an important addition to our blog page, adding the scientific answers to our Isala kit conversation starters.

June 28, 2020
July 2020

Isala kits leave …

More than 4,150 kits from Isala were sent. We invite all women to take samples. Our social media exploded thanks to countless tags and stories.

… And return

The samples are pouring in. This citizen science project is a great success. We have received samples from 3332 women! Now to start the analyses!

August 2020
August 2020

Preparation in our lab

We welcome robot Rey, who will help us process all samples, fortunately, because there is a lot of work.

Ready for phase two

Based on a complex scientific algorithm, we have selected 500 women eligible for the second phase of our research. We consult intensively about this with biostatisticians and other scientists. Using several swabs over two cycles, we want to learn even more about the influence of birth control, hormones, nutrition, and personal hygiene on the vaginal microbiome. We even hope to collect data to help with a breakthrough in forensics. 

September 2020
October 2020

The large Isala kits are shipped

In the end, we choose 275 women. They received the pink, large Isala kit in their Postal box. They were asked to take swabs from their skin, vagina and saliva.

The analyses continue 

These are super exciting weeks at our lab. The DNA analysis of all swabs continues, and we are busy checking hypotheses and writing history. By Friday, October 30, we had already examined 1,526 samples, keeping up the hard work! 

Fall 2020
January 2021

The samples from phase 2 are pouring in

Now we investigate the dynamics of the vaginal microbiome in 275 women. They also donate three skin samples and one saliva sample.

Isala goes international! Get to know Laura in Peru!

We will study the vaginal microbiome in Peru’s Amazon and Coastal regions! We are working in collaboration with Universidad Nacional de la Amazonía Peruana and Universidad Peruana Cayetano Heredia.

March 2021
April 2021

At full throttle

The lab is still running at full capacity. We continue analyzing swabs and also growing bacteria. And for  the very first time in our lab, we managed to isolate Lactobacillus iners. This could really be a milestone for further research on this common vaginal bacteria

A wealth of data

Thanks to more than 3300 women who participated in the first research phase of Isala, we have a wealth of data. We have many intensive consultations with microbiologist, doctors, statisticians, and communication specialists. Together we make the right choices to inform our participants about their individual results.

May 2021
June 2021

Almost…

We are almost ready to share a year of hard work with the world. We like to pamper Isala’s participants, so we are working hard to combine our lab work with the preparations for communication to the general public, scientist and of course our participants.
Fortunately, Isala can count on a fantastic team!

The first results arrived!

Discover here what we have already learned about the vaginal microbiome in Flanders

June 2021